Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.

Desloratadine
| Description | |
|---|---|
| 8-chloro-6,11-dihydro-11-(4-piperdinylidene)- 5H-benzo[5,6]cyclohepta[1,2-b]pyridine | |
| 100643-71-8 | |
| C19H19CIN2 | |
| Allex;Aerius;AzoMyr;Opulis;Clarinex;SCH-34117;AKOS 92131;NSC 675447;Neoclarityn;DESLORATIDINE | |
| For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria. | |