Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM).
Loratadine
| Description | |
|---|---|
| Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate | |
| 79794-75-5 | |
| C22H23CIN2O2 | |
| Lisino;Tadine;Civeran;Loranox;CLARITIN;Clarityn;CLARATYNE;SCH-29851;Claritine;LORATADINE | |
| Anti-histamine | |
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